Iran has issued strong warnings to the U.S. and Israel, with its supreme leader, Ayatollah Ali Khamenei, vowing a “tooth-breaking response” and top officials hinting at potential changes to Iran’s nuclear policy if faced with existential threats.

Khamenei declared on Saturday that Iran would retaliate forcefully against Israel and the United States for “what they are doing against Iran” and its allies in the region. The remarks follow an intensifying cycle of military exchanges and political posturing that has stoked fears of further escalation.

Kamal Kharrazi, a senior adviser to Khamenei, suggested on Friday that Iran could shift its nuclear policy to create weapons. Speaking to Lebanese broadcaster Al Mayadeen, Kharrazi stated that Iran has the capacity to develop nuclear weapons and may reconsider its stance on nuclear arms should the nation face an existential threat.

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